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Optimizing the use of cryopreserved genetic resources for animal populations in breeding and conservation

How can cryopreserved animal genetic resources be used? Simulation work has shown that the use of cryopreserved genetic resources can not only slow down the loss of genetic diversity in populations, but also support changes in breeding objectives. The use of these resources varies according to the objective of the population manager. This study provides practical recommendations for different management scenarios.

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Genetic diversity is essential for the sustainability of breeding systems, especially in a context of agro-ecological transition.

To prevent the erosion of this diversity, genebanks that store cryopreserved genetic material for reproductive purposes represent valuable resources. The study, based on simulations of selection and conservation schemes, examines different management scenarios for breeding populations. In populations subject to a conservation program, the regular use of cryopreserved seed from former breeders helps preserve genetic diversity. For selected populations, cryopreserved seeds are useful for reintroducing genetic variability or for accompanying a change in selection objectives. However, the use of cryopreserved seed must be moderated and reasoned to avoid a negative impact on genetic values due to an unavoidable delay in selected traits. The use of OCS (i.e. Optimal Contribution Selection) makes it possible to reconcile genetic progress and diversity conservation. The study stresses the need for sufficient stocks of cryopreserved resources to enable the best possible selection of resources for reuse, demonstrating the necessity of continuing to feed ex situ collections.

Contact : Alicia Jacques (alicia.jacques@eliance.fr)

Reference

Jacques, A., M. Tixier-Boichard, and G. Restoux. 2025. “ Optimising the Use of Cryopreserved Genetic Resources for the Selection and Conservation of Animal Populations.” Journal of Animal Breeding and Genetics 1–18. https://doi.org/10.1111/jbg.70000